COLLAGEN DISEASES – PROGRESSIVE SYSTEMIC SCLEROSIS
Posted on May 15, 2009 under General health | No CommentScleroderma or Progressive Systemic Sclerosis is another of the collagen diseases. It is characterised by an increase in the collagen fibres of connective tissue which leads to obliteration of small arteries.
It usually starts in the skin but may later spread to other organs. The digestive tract, the lungs, the kidneys and the heart may all be involved.
The cause of this disorder, like SLE, is thought to be an auto-immune disease. Occasionally it may have an acute onset with rapid progression to an early death, but, more commonly, it is a slowly progressive disorder.
When the gullet or oesophagus is involved, the scarring causes obstruction and difficulty in swallowing.
Treatment is unsatisfactory and cortisone is of little benefit.
Polyarteritis Nodosa differs from the other collagen diseases in that it is rare and affects males three times as commonly as females. It may occur at any age.
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